Strategic Research

Evolutionary Systems Biology

Our present main research focuses on the understanding of natural selection and adaptation in humans and in primates through the comparative analysis of genomes. Our purpose is the understanding of complex adaptations by genome wide analyses of the footprints that natural selection has left in the genomes after its action and not only detecting single signals (in one specific gene or genome region) but trying to put selection in a functional molecular framework of molecular pathways. We use and develop bioinformatic tools to answer these questions.

Main projects

  • 1.

    Footprints of adaptation in humans and purifying selection in higher primates

  • 2.

    Human population genetics and recombination

  • 3.

    Human genetic diversity and population history



Bioinformatics expertise:

Group Leader:

Jaume Bertranpetit


Judit Sainz