Postdoctoral Fellow in the Targeted Protein Degradation & Drug Discovery Lab (ref. PD/21/25)

Centre / Institution:
Institute for Research in Biomedicine (IRB Barcelona)
Bioinformatics expertise:
Biomedical Informatics

Job description

IRB Barcelona is seeking a postdoctoral scientist who wants to develop and apply cutting-edge technology for biomedical research in the growing field of targeted protein degradation. Our lab pursues highly multidisciplinary and collaborative research at the interface of molecular biology, functional genetics, medicinal chemistry and bioinformatics.

The postdoctoral candidate should have a proactive mindset, be able to work in a molecular biology lab and be willing to collaborate with colleagues from the pharmaceutical industry. Great experience in gene engineering, cell-based assays and chemical screen optimization are required. The postdoc will champion an ambitious drug discovery project in collaboration with the pharma sector.


  • Conduct independent research in chemical biology/targeted protein degradation.
  • Cell engineering, screen optimization.
  • Report writing.

Desired skills and expertise

Must Have - Required


  • PhD in molecular biology/bioscience/chemical biology or similar.
  • Experience in data analysis in at least one field of systems biology research (genomics, transcriptomics, proteomics, metabolomics, high-content imaging, ...)
  • Required are scientific quality and a collaborative and interdisciplinary mindset.
  • Experience in a competitive research environment.


  • Molecular biology, functional genomics, chemical biology, CRISPR/Cas9.
  • Chemical biology background is a plus.


  • Ability to work in a team and pursue goals in a focused way.
  • Excellent written/oral communication skills in English.



  • Drug and genetic screens.
  • Proteomics.
  • Biochemistry/structural biology.


  • Targeted protein degradation, PROTACs/molecular glues, chemistry background is a plus.

Contract duration and other benefits


  • Training and Career: Postdoctoral researchers joining IRB Barcelona gain access to the Institute's advanced research training and career development opportunities, all within in a competitive international environment. Courses and workshops on themes of particular interest to postdocs are offered regularly by the Institute.
  • International environment: Nearly 90 Postdoctoral researchers (more than a half non-Spanish nationals) are currently working at IRB Barcelona.

Required information and contact

Applications for the above opening should include a motivation letter explaining why you are the ideal candidate for this position, your curriculum vitae and contact details of 2-3 referees, and should apply on Reference: PD/21/25

  • Deadline for applications: 23/12/2021

If no suitable candidate is found, the deadline will be extended.  

  • Number of positions available: 1

Selection process:

  • Pre-selection: Will be based on CV, motivation letter, experience, management of research and innovation.
  • Interviews: Short-listed candidates will be interviewed.
  • Job offer: Will be sent to the successful candidate after the interview. 

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